Rikard Holmdahl Selected Research

Epitopes

1/2022	Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology.
1/2021	Emerging glyco-based strategies to steer immune responses.
1/2020	Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis.
12/2018	Regulatory T cells control epitope spreading in autoimmune arthritis independent of cytotoxic T-lymphocyte antigen-4.
1/2018	Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants.
1/2018	A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis.
7/2017	Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
1/2016	Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis.
10/2015	An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.
8/2015	B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

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Rikard Holmdahl Research Topics

Disease

167	Arthritis (Polyarthritis) 12/2022 - 01/2002
123	Rheumatoid Arthritis 12/2022 - 02/2002
77	Experimental Arthritis 01/2021 - 05/2002
52	Inflammation (Inflammations) 12/2022 - 01/2002
35	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2002
11	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2022 - 10/2006
9	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 05/2017 - 07/2002
7	Neoplasms (Cancer) 01/2022 - 10/2010
6	Infections 12/2022 - 09/2014
6	Hypersensitivity (Allergy) 01/2022 - 08/2004
6	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 09/2002
6	Multiple Sclerosis 05/2017 - 01/2003
5	Psoriatic Arthritis 12/2022 - 09/2016
5	Pain (Aches) 01/2022 - 12/2012
5	Chronic Granulomatous Disease 12/2014 - 11/2012
4	Necrosis 01/2021 - 08/2005
4	Pneumonia (Pneumonitis) 01/2021 - 04/2013
4	Colitis 03/2018 - 01/2014
4	Relapsing Polychondritis 03/2004 - 01/2002
3	Chronic Disease (Chronic Diseases) 05/2022 - 08/2011
3	Pathologic Processes 09/2016 - 01/2010
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016 - 09/2011
2	Periodontitis 01/2022 - 11/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2018 - 10/2016

Drug/Important Bio-Agent (IBA)

88	Collagen Type II (Type II Collagen)IBA 05/2022 - 01/2002
59	AntibodiesIBA 01/2022 - 09/2002
41	CollagenIBA 12/2022 - 01/2002
41	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
37	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2021 - 09/2005
35	EpitopesIBA 01/2022 - 06/2002
33	pristane (pristan)IBA 01/2021 - 01/2002
32	Peptides (Polypeptides)IBA 01/2022 - 01/2003
31	AutoantibodiesIBA 05/2022 - 09/2002
24	Immunoglobulin G (IgG)IBA 10/2020 - 09/2002
22	AntigensIBA 01/2022 - 08/2005
21	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2020 - 01/2003
17	CytokinesIBA 01/2021 - 10/2002
13	Monoclonal AntibodiesIBA 05/2022 - 09/2002
13	AutoantigensIBA 01/2022 - 01/2002
12	MannansIBA 12/2022 - 09/2014
11	neutrophil cytosolic factor 1IBA 05/2022 - 01/2003
11	Anti-Citrullinated Protein AntibodiesIBA 01/2022 - 01/2010
11	acetyl 4-aminosalicylic acidIBA 10/2020 - 01/2010
11	GlycopeptidesIBA 01/2018 - 12/2002
9	Cartilage Oligomeric Matrix ProteinIBA 01/2022 - 01/2002
8	Polysaccharides (Glycans)IBA 12/2022 - 10/2007
8	Antigen-Antibody Complex (Immune Complex)IBA 01/2019 - 07/2004
8	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2017 - 06/2002
8	Histocompatibility Antigens Class IIIBA 11/2012 - 01/2006
7	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 12/2002
6	VaccinesIBA 01/2022 - 10/2010
6	EnzymesIBA 11/2017 - 03/2006
5	HLA-DRB1 Chains (HLA DRB1)IBA 01/2022 - 01/2006
5	Rheumatoid FactorIBA 10/2020 - 12/2003
5	Oxygen (Dioxygen)IBA 01/2020 - 08/2007
5	Complement System Proteins (Complement)IBA 10/2013 - 03/2004
4	Collagen Type XIIBA 01/2020 - 05/2002
4	Glycoproteins (Glycoprotein)IBA 01/2020 - 01/2002
4	InterferonsIBA 01/2020 - 07/2013
4	LipopolysaccharidesIBA 01/2020 - 11/2003
4	Immunoglobulin M (IgM)IBA 01/2020 - 12/2003
4	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 12/2018 - 01/2005
4	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 01/2010
4	Mineral Oil (Liquid Paraffin)FDA LinkGeneric 11/2017 - 12/2007
4	Biological ProductsIBA 10/2016 - 09/2006
4	Amino Acids FDA Link 03/2015 - 09/2002
4	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 11/2012 - 02/2007
4	NADP (NADPH)IBA 07/2012 - 09/2005
3	glycosylated collagenIBA 01/2022 - 07/2002
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2007
3	Therapeutic UsesIBA 01/2021 - 07/2004
3	LipidsIBA 01/2021 - 11/2017
3	LigandsIBA 10/2020 - 08/2010
3	NitrogenIBA 01/2020 - 09/2009
3	Interleukin-17 (Interleukin 17)IBA 01/2020 - 01/2017
3	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 12/2018 - 08/2015
3	SodiumIBA 03/2018 - 08/2014
3	AsparagineIBA 01/2018 - 10/2007
3	Acute-Phase Proteins (Acute-Phase Protein)IBA 11/2017 - 01/2002
3	Proteoglycans (Proteoglycan)IBA 07/2017 - 06/2011
3	Estrogens (Estrogen)FDA Link 11/2016 - 11/2003
3	NADPH Oxidase 2IBA 11/2016 - 05/2012
3	poly-N-isopropylacrylamideIBA 01/2016 - 11/2011
3	PolymersIBA 01/2016 - 11/2011
3	CitrullineIBA 10/2015 - 02/2009
3	Immunodominant EpitopesIBA 11/2014 - 01/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2006 - 02/2002
3	Myelin-Oligodendrocyte GlycoproteinIBA 08/2004 - 07/2002
2	GlucansIBA 12/2022 - 04/2013
2	CholesterolIBA 01/2021 - 01/2016
2	Oxidants (Oxidizing Agents)IBA 01/2019 - 04/2013
2	Dextrans (Dextran)FDA Link 03/2018 - 08/2014
2	Nucleic AcidsIBA 01/2018 - 11/2017
2	Acetylglucosaminidase (NAGase)IBA 01/2018 - 06/2013
2	Dextran SulfateIBA 01/2018 - 01/2014

Therapy/Procedure

8	Therapeutics 01/2021 - 02/2002
4	Injections 05/2022 - 03/2005
3	Intravenous Injections 05/2022 - 07/2004
3	Intraperitoneal Injections 01/2018 - 09/2005
3	Transplantation 10/2010 - 06/2002